Science

Asking cells direct, physical questions

Senior Lab Research Scientist (Translation Scholar) at the Francis Crick Institute, developing intracellular magnetic tweezers (MeTS). Visiting lecturer at UCL's GBSH course.

Publications

• Measuring molecular forces inside living cells using magnetic tweezers

  Kongari, A. & Molodtsov, M. — Biophysical Reviews, 17(4), 2025

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• Micron-scale electromagnetic tweezers for intracellular force application

  Kongari, A. P. — Doctoral thesis (PhD), UCL (University College London), 2024

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Instruments & techniques

Core technique

Intracellular magnetic tweezers (MeTS) — applying and measuring piconewton-scale forces inside living cells using sub-100 nm magnetic nanoparticles.

Microscopy

TIRF, spinning disk confocal, scanning ion conductance microscopy (SICM).

Image analysis

ImageJ / Fiji-based quantification and processing pipelines, including custom Fiji macro scripts.

Instrumentation

LabVIEW-based control systems for custom experimental setups, with Python and MATLAB for data acquisition and analysis.

Articles

Notes from the lab

• Research

  MeTS: measuring forces inside living cells

  A platform for applying and measuring piconewton-scale forces inside living cells, using sub-100 nanometre magnetic nanoparticles — a way of asking cells direct, physical questions.